Therapeutic Effects of Lactoferrin in Ocular Diseases: From Dry Eye Disease to Infections
نویسندگان
چکیده
منابع مشابه
Dry Eye: an Inflammatory Ocular Disease
Keratoconjunctivitis sicca, or dry eye, is a common ocular disease prompting millions of individuals to seek ophthalmological care. Regardless of the underlying etiology, dry eye has been shown to be associated with abnormalities in the pre-corneal tear film and subsequent inflammatory changes in the entire ocular surface including the adnexa, conjunctiva and cornea. Since the recognition of th...
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1Pharmacology & Pharmaceutical Sciences, USC Eye Institute, University of Southern California, Los Angeles, CA, USA 2Pharmacology and Pharmacotherapy, Ophthalmology, University of Szeged, Szeged, Hungary 3Ophthalmology, Beijing Tongren Hospital, Beijing Institute of Ophthalmology, Beijing, China 4Singapore Eye Research Institute, Singapore 5Department of Ophthalmology, Yong Loo Lin School of Me...
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PURPOSE Th17 cells are believed to be the primary effector cells in the pathogenesis of dry eye disease (DED). However, the mechanisms by which Th17 cells migrate from the lymphoid tissues to the ocular surface are unknown. The purpose of this study was to investigate the role of the C-C chemokine receptor 6/C-C chemokine ligand 20 (CCR6/CCL20) chemokine axis in mediating Th17 cell migration in...
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ژورنال
عنوان ژورنال: International Journal of Molecular Sciences
سال: 2020
ISSN: 1422-0067
DOI: 10.3390/ijms21186668